ABSTRACT
Over recent decades, environmental pollution is rapidly increasing because of the anthropogenic activities of uncontrolled development, for example, industry, transport, agriculture, and urbanization, which generates harmful contaminants for living organisms including humans. These contaminants get accumulated in the organism via different routes and get bioaccumulated in different tissues exerting detrimental effects at different levels (molecular, cellular and physiological levels). The measurement of biological assays in sentinel species to access quality and changes of the environment is known as environmental biomonitoring which provides an indication of environmental stress. Several biomarkers evaluate the nature and extent of the exposure and evaluation of adverse biological responses to pollutants in a biomonitoring program of the aquatic environment. These include behavioral response, genotoxicity (comet assay and micronucleus assay) and oxidative stress. Here we present the importance of these biomarkers.
AUTHOR AFFILIATIONS
PG Department of Zoology, Khalsa College Amritsar, Punjab, India 143001
Department of Zoology, Guru Nanak Dev University, Amritsar, Punjab, India 143001
Correspondence and requests for materials should be addressed to PC
CITATION
Mehra S and Chadha P (2023) Molecular Biomarkers as Key Factors to Evaluate the Extent of Industrial Pollution Exposure. Environ Sci Arch 2(STI-2):18-22.
REFERENCES
1. Alimba CG, Ajiboye RD and Fagbenro OS (2017) Dietary ascorbic acid reduced micronucleus and nuclear abnormalities in Clarias gariepinus (Burchell 1822) exposed to hospital effluent. Fish Physiology and Biochemistry 43(5): 1325–1335. DOI: 10.1007/s10695-017-0375-y.
2. Ateeq B, Farah MA and Ahmad W (2005) Detection of DNA damage by alkaline single cell gel electrophoresis in 2,4-dichlorophenoxyacetic-acid- and butachlor-exposed erythrocytes of Clarias batrachus. Ecotoxicology and Environmental Safety 62(3): 348–354. DOI: 10.1016/J.ECOENV.2004.12.011.
3. Atli G, Alptekin Ö, Tükel S, et al. (2006) Response of catalase activity to Ag+, Cd2+, Cr6+, Cu2+ and Zn2+ in five tissues of freshwater fish Oreochromis niloticus. Comparative Biochemistry and Physiology - C Toxicology and Pharmacology 143(2): 218–224. DOI: 10.1016/j.cbpc.2006.02.003.
4. Mansour M, El-Kashoury A, Rashed M, et al. (2009) Oxidative and biochemical alterations induced by profenofos insecticide in rats. Nature and Science 7(2): 1-15.
5. Mohanty G, Mohanty J, Nayak AK, et al. (2011) Application of comet assay in the study of DNA damage and recovery in rohu (Labeo rohita) fingerlings after exposure to phorate, an organophosphate pesticide. Ecotoxicology 20(1): 283–292. DOI: 10.1007/s10646-010-0580-2.
6. Osterauer R, Faßbender C, Braunbeck T, et al. (2011) Genotoxicity of platinum in embryos of zebrafish (Danio rerio) and ramshorn snail (Marisa cornuarietis). Science of the Total Environment 409(11): 2114–2119. DOI: 10.1016/j.scitotenv.2011.01.060.
7. Pandey AK, Nagpure NS, Trivedi SP, et al. (2011) Investigation on acute toxicity and behavioral changes in Channa punctatus (Bloch) due to organophosphate pesticide profenofos. Drug and Chemical Toxicology 34(4): 424–428. DOI: 10.3109/01480545.2011.585650.
8. Parmar A and Shah A (2019) Cytogenotoxicity of azo dye Reactive Red 120 (RR120) on fish Catla catla. Environmental and Experimental Biology 17(3): 151–155. DOI: 10.22364/eeb.17.15.
9. Rishin A, Priyatha C V and Chitra KC (2019) Induction of genetic damage in peripheral erythrocytes of the fish, Anabas testudineus exposed to sublethal concentration of Acid Orange 7. Research & Reviews: A Journal of Life Sciences 9(2): 1–10.
10. Sharma M, Chadha P and Borah MK (2018) Histological alterations induced by 4-Nonylphenol in different organs of fish, Channa punctatus after acute and sub-chronic exposure. Journal of Entomology and Zoology Studies 6(4): 492–499.
11. Song SB, Xu Y and Zhou BS (2006) Effects of hexachlorobenzene on antioxidant status of liver and brain of common carp (Cyprinus carpio). Chemosphere 65(4): 699–706. DOI: 10.1016/j.chemosphere.2006.01.033.
12. Stara A, Kristan J, Zuskova E, et al. (2013) Effect of chronic exposure to prometryne on oxidative stress and antioxidant response in common carp (Cyprinus carpio L.). Pesticide Biochemistry and Physiology 105(1): 18–23. DOI: 10.1016/j.pestbp.2012.11.002.
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