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Monocrotophos Induced Changes in the Life Cycle Parameters of Fruit Fly

Kanchana Das 1, Shanta Pramanik 1, Prem Rajak 2, Gopal Biswas 1 and Moutushi Mandi 1


DOI: 10.5281/zenodo.10838406


Current study investigated the chronic effect of monocrotophos exposure, a globally used pesticide on 3rd instar larvae and pupae of fruit fly Drosophila melanogaster. Study commenced with the investigation of chronic median lethal concentration (LC50) which was found as 0.68 µg/mL for 3rd instar larvae and 0.56 µg/mL for pupae. Accordingly five sub-lethal concentrations such as 0.2, 0.25, 0.3, 0.35 and 0.4 µg/mL were selected for experimental set up. Treated larvae manifested altered feeding habit, changed life cycle duration and reduced body weight and length in both larval and pupal stage. Interestingly alteration in sex-ratio and gender biased population was encountered after exposure to monocrotophos. Since D. melanogaster shares significant molecular and physiological homologies with higher vertebrates, hence the present findings could be alarming for other non-targeted organisms who are getting direct or indirect chronic exposure to this chemical.


1 Toxicology Research Unit, Department of Zoology, The University of Burdwan, West Bengal, India
2 Kazi Nazrul University, Asansol, West Barddhaman, West Bengal, India



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